太赫兹场存在下的DNA呼吸动力学
DNA Breathing Dynamics in the Presence of a Terahertz Field
摘要:
我们考虑太赫兹场对双链DNA呼吸动力学的影响。我们模拟阻尼和驱动DNA链的空间局部开口的自发形成,发现线性不稳定性导致动态二聚化,而真正的局部链分离需要阈值振幅机制。基于我们的研究结果,我们认为,特定的太赫兹辐射暴露可能会显着影响DNA的自然动力学,从而影响基因表达和DNA复制中涉及的复杂分子过程。
英文摘要:
We consider the influence of a terahertz field on the breathing dynamics of double-stranded DNA. We model the spontaneous formation of spatially localized openings of a damped and driven DNA chain, and find that linear instabilities lead to dynamic dimerization, while true local strand separations require a threshold amplitude mechanism. Based on our results we argue that a specific terahertz radiation exposure may significantly affect the natural dynamics of DNA, and thereby influence intricate molecular processes involved in gene expression and DNA replication.
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