用于便携式生物医学微流体的超快高压AC电渗泵
Ultrafast High-pressure AC Electro-osmotic Pumps for Portable Biomedical Microfluidics
摘要：
本文详细介绍了一种集成的交流电渗（ACEO）微流体泵的稀电解质组成的一个长的蛇形微通道内衬三维（3D）阶梯电极阵列的发展。在水中使用低AC电压（1伏特rms，1 kHz）、功率（5 mW）和电流（3.5 mA），该泵能够产生1.4 kPa的压头，比现有的ACEO泵增加100倍，并且在电极上的有效滑动速度为1.37 mm/sec而没有流动反向。集成ACEO泵可以利用低离子强度溶液如蒸馏水作为工作溶液，以泵送单独的微流体装置中的生理强度（100 mM）生物溶液，具有便携式或可植入生物医学微流体装置中的潜在应用。作为一个概念验证的实验，使用ACEO泵的DNA杂交在微流控微阵列的证明。
英文摘要：
This paper details the development of an integrated AC electro-osmotic (ACEO) microfluidic pump for dilute electrolytes consisting of a long serpentine microchannel lined with three dimensional (3D) stepped electrode arrays. Using low AC voltage (1 Volt rms, 1 kHz), power (5 mW) and current (3.5 mA) in water, the pump is capable of generating a 1.4 kPa head pressure, a 100-fold increase over prior ACEO pumps, and a 1.37 mm/sec effective slip velocity over the electrodes without flow reversal. The integrated ACEO pump can utilize low ionic strength solutions such as distilled water as the working solution to pump physiological strength (100 mM) biological solutions in separate microfluidic devices, with potential applications in portable or implantable biomedical microfluidic devices. As a proof-of-concept experiment, the use of the ACEO pumps for DNA hybridization in a microfluidic microarray is demonstrated.
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