用皮米高度分辨率的陆地对比度干涉测量法测量二氧化硅上的分子水积累
Molecular water accumulation on silica measured by land-contrast interferometry with picometer height resolution
摘要：
我们观察到的水膜积累在空气中的二氧化硅表面上的2皮米分辨率使用光学地面对比度（LC）干涉。地面对比方法是非破坏性的，并且允许实时测量表面上小分子膜的厚度变化。水的积累率被观察到是不同的裸露或蛋白质单层涂覆的二氧化硅表面。这表明水对蛋白质微阵列的质量敏感生物传感器产生错误信号。
英文摘要：
We observed water film accumulation on silica surfaces in the air to 2 picometer resolution using optical land-contrast (LC) interferometry. The land-contrast approach is non-destructive and allows real-time measurement of thickness variation of small molecular films on a surface. Water accumulation rates are observed to be different on bare or protein monolayer coated silica surfaces. This suggests that water contributes false signals to mass-sensitive biosensors for protein microarray.
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