双足纳米电动机的协同机理及制备目标
Synergic mechanism and fabrication target for bipedal nanomotors
摘要：
受到能够在活细胞中进行运输的二聚马达蛋白的启发，已经花费了大量的努力来制造具有两个脚样组件的履带行走纳米马达，每个组件可以响应于试剂消耗的局部事件而结合或脱离履带上的锚定基团阵列。制造双足纳米电机的核心问题是电机作为一个整体如何获得定向履带行走的协同能力，因为每个踏板组件通常无法单独进行任何方向漂移。迄今为止实施的双足马达通过直观的策略解决了这个复杂的问题，该策略需要异足马达、用于轨道的多个锚定物种以及用于马达操作的多个试剂物种。在这里，我们提出了一个详细的分子机制，电机水平的方向性产生的homo-pedal电机沿最低限度的异构轨道。最佳地，操作可以减少到随机供应单一种类的试剂以允许马达的自主功能。该机制表明了一种明显降低系统要求的制造目标。有趣的是，该机制的缺陷形式落入众所周知的布朗电机机制的领域，但从该机制的正常工作中出现了明显的特征。
英文摘要：
Inspired by dimeric motor proteins capable of undergoing transportation in living cells, significant efforts have been expended to the fabrication of track-walking nanomotors possessing two foot-like components that each can bind or detach from an array of anchorage groups on the track in response to local events of reagent consumption. The central problem in fabricating bipedal nanomotors is how the motor as a whole can gain the synergic capacity of directional track-walking, given the fact that each pedal component alone often is incapable of any directional drift. Implemented bipedal motors to date solve this thermodynamically intricate problem by an intuitive strategy that requires a hetero-pedal motor, multiple anchorage species for the track, and multiple reagent species for motor operation. Here we presented a detailed molecular mechanism by which motor-level directionality arises from a homo-pedal motor along a minimally heterogeneous track. Optimally, the operation may be reduced to a random supply of a single species of reagents to allow the motor's autonomous functioning. The mechanism suggests a distinct class of fabrication targets of drastically reduced system requirements. Intriguingly, a defective form of the mechanism falls into the realm of the well known Brownian motor mechanism, yet distinct features emerge from the normal working of the mechanism.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
