通过畴壁管道实现磁性粒子的片上纳米操纵
On-chip nano-manipulation of magnetic particles via domain walls conduits
摘要：
纳米级磁条中的几何约束磁畴壁（DW）的操纵最近引起了人们的极大兴趣，并提出了用于预期存储器和逻辑器件的建议。在这里，我们建议使用高可控性的几何约束DW的运动，用于在芯片上的单个纳米粒子的操作与主动控制的位置在纳米尺度。所提出的方法利用了这样一个事实，即溶液中的磁性纳米颗粒可以被DW捕获，DW的位置可以在专门设计的磁性纳米线结构中以纳米精度进行操纵。我们表明，在这种结构中的DW成核，位移和湮灭过程的高度控制，可用于捕获，运输和释放磁性纳米粒子。由于具有功能化表面的磁性颗粒通常在几种应用中用作分子标记-包括单分子操纵、分离、细胞操纵和生物磁性感测，因此对单个磁性纳米颗粒的处理的准确控制变得至关重要，因为它可以反映单个分子的处理。这里描述的方法打开了纳米传输线的实现和设计的道路，并应用于单分子研究和芯片实验室设备。在透视图中，容易集成在芯片上的域壁和颗粒的传感器将允许实现可编程电路的分子操作与所需的过程的连续控制。
英文摘要：
The manipulation of geometrically constrained magnetic domain walls (DWs) in nanoscale magnetic strips has attracted much interest recently, with proposals for prospective memory and logic devices. Here we propose to use the high controllability of the motion of geometrically constrained DWs for the manipulation of individual nanoparticles on a chip with an active control of position at the nanometer scale. The proposed method exploits the fact that magnetic nanoparticles in solution can be captured by a DW, whose position can be manipulated with nanometric accuracy in a specifically designed magnetic nanowire structure. We show that the high control over DW nucleation, displacement, and annihilation processes in such structures can be used to capture, transport and release magnetic nanoparticles. As magnetic particles with functionalized surfaces are commonly used as molecule labels in several applications - including single molecule manipulation, separation, cells manipulation and biomagnetic sensing, the accurate control over the handling of the single magnetic nanoparticles becomes crucial as it may reflect the handling of the single molecules. The approach described here opens the path to the implementation and design of nano-transport lines, with application to single molecule study and lab-on-chip devices. In perspective, the easy integration on chip with sensors of domain walls and particles will allow for the realization of programmable circuits for molecular manipulation with continuous control of the desired process.
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