与分流抑制同步
Synchrony with Shunting Inhibition
摘要:
在没有弱耦合假设的情况下,利用尖峰时间响应曲线(STRC)研究了突触刺激对神经元振子放电时间的影响。它们允许我们通过离散映射来近似神经元网络中同步状态的动态。关于离散映射的不动点的线性化可以用来预测网络中同步模式的稳定性。一般的理论,考虑到高阶STRC项的贡献,在近似的离散映射的耦合神经元振子的同步仍然缺乏。在这里,我们提出了一个一般的框架来考虑高阶STRC校正的离散映射的近似,以确定在两个相互作用的神经元网络中的1:1锁相状态的域。我们首先证明,通过分流突触的突触刺激的影响,神经元发射在伽马频带(20-80 Hz)持续三个连续的发射周期。然后,我们表明,通过考虑到高阶STRC贡献的离散映射是成功地能够预测域的同步1:1锁相状态的两个异构的interneurons通过分流突触耦合的网络。
英文摘要:
Spike time response curves (STRC's) are used to study the influence of synaptic stimuli on the firing times of a neuron oscillator without the assumption of weak coupling. They allow us to approximate the dynamics of synchronous state in networks of neurons through a discrete map. Linearization about the fixed point of the discrete map can then be used to predict the stability of patterns of synchrony in the network. General theory for taking into account the contribution from higher order STRC terms, in the approximation of the discrete map for coupled neuronal oscillators in synchrony is still lacking. Here we present a general framework to account for higher order STRC corrections in the approximation of discrete map to determine the domain of 1:1 phase locking state in the network of two interacting neurons. We begin by demonstrating that the effect of synaptic stimuli through a shunting synapse to a neuron firing in the gamma frequency band (20-80 Hz) last for three consecutive firing cycles. We then show that the discrete map derived by taking into account the higher order STRC contributions is successfully able predict the domain of synchronous 1:1 phase locked state in a network of two heterogeneous interneurons coupled through a shunting synapse.
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