微结构通道中流体囊泡的动力学特性
Dynamics of Fluid Vesicles in Flow through Structured Microchannels
摘要：
研究了微通道中流体囊泡的动力学行为，微通道的宽度沿通道呈周期性变化。三种类型的流动不稳定性的扁长囊泡被发现。对于小的准球形囊泡-相比，平均通道宽度-微扰理论预测的过渡状态与取向振荡的一个固定的扁长形的形状与对称的椭圆形或子弹状的形状振荡的状态，随着流速的增加。实验上，这种取向的振荡过程中观察到的缓慢迁移的囊泡对通道的中心线。对于较大的囊泡，中尺度流体动力学模拟和实验表明，在减少体积$V^* \gtrsim 0.9$类似的对称形状振荡。然而，对于具有$V^* \lesssim 0.9$的非球形囊泡，发现具有两个对称或单个不对称尾部的形状。
英文摘要：
The dynamics of fluid vesicles is studied under flow in microchannels, in which the width varies periodically along the channel. Three types of flow instabilities of prolate vesicles are found. For small quasi-spherical vesicles -- compared to the average channel width -- perturbation theory predicts a transition from a state with orientational oscillations of a fixed prolate shape to a state with shape oscillations of symmetrical ellipsoidal or bullet-like shapes with increasing flow velocity. Experimentally, such orientational oscillations are observed during the slow migration of a vesicle towards the centerline of the channel. For larger vesicles, mesoscale hydrodynamics simulations and experiments show similar symmetric shape oscillation at reduced volumes $V^* \gtrsim 0.9$. However, for non-spherical vesicles with $V^* \lesssim 0.9$, shapes are found with two symmetric or a single asymmetric tail.
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