脂质囊泡中聚合物诱导的微管蛋白
Polymer-induced tubulation in lipid vesicles
摘要：
提出了从脂质囊泡中提取管状膜的机制。锚定两亲聚合物的浓度梯度从芽状囊泡突起产生管。我们解释这个机制的框架下的Canham-Helfrich模型。的能量分布进行了分析计算和一个固定的长度，对应于一个能量最小值的管，得到在一定的制度的参数。此外，使用相场模型，我们证实了这些结果的数值。我们得到的增长管时，聚合物源被添加，和芽状形状后，删除的聚合物源，根据最近的实验结果。
英文摘要：
A mechanism of extraction of tubular membranes from a lipid vesicle is presented. A concentration gradient of anchoring amphiphilic polymers generates tubes from bud-like vesicle protrusions. We explain this mechanism in the framework of the Canham-Helfrich model. The energy profile is analytically calculated and a tube with a fixed length, corresponding to an energy minimum, is obtained in a certain regime of parameters. Further, using a phase-field model, we corroborate these results numerically. We obtain the growth of tubes when a polymer source is added, and the bud-like shape after removal of the polymer source, in accordance with recent experimental results.
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