血管和主动脉弓中脉动人体血液流动的三维计算机模拟：人体血液非牛顿特性的研究
3D Computer Simulations of Pulsatile Human Blood Flows in Vessels and in the Aortic Arch: Investigation of Non-Newtonian Characteristics of Human Blood
摘要：
本文应用计算流体动力学方法模拟了人体血管和主动脉弓中的脉动血流，研究了人体血液在实际尺寸的简单血管中的非牛顿行为。一个详细的时间相关的数学收敛性测试已经进行。在所有模拟中使用真实的脉动流。两种不同的几何形状的血管中的血液流动的计算机模拟的结果。对于压力，应变率和速度分量分布，我们发现我们的结果与现实的非牛顿治疗人类血液和文献中广泛使用的方法：一个简单的牛顿近似之间的显着分歧。一个显着增加的应变率，因此，壁烧灼应力分布，被发现在该地区的主动脉弓。我们认为这一结果作为理论证据，支持现有的临床观察和那些不使用非牛顿治疗模型低估了破坏人体血管系统的风险。
英文摘要：
Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed time-dependent mathematical convergence test has been carried out. The realistic pulsatile flow is used in all simulations. Results of computer simulations of the blood flow in vessels of two different geometries are presented. For pressure, strain rate and velocity component distributions we found significant disagreements between our results obtained with realistic non-Newtonian treatment of human blood and widely used method in literature: a simple Newtonian approximation. A significant increase of the strain rate and, as a result, wall sear stress distribution, is found in the region of the aortic arch. We consider this result as theoretical evidence that supports existing clinical observations and those models not using non-Newtonian treatment underestimate the risk of disruption to the human vascular system.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
