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arXiv 0802.1107physics.comp-phphysics.bio-ph
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生物聚合物通过纳米孔移位的量化电流阻断和流体动力学相关性:来自多尺度模拟的证据

Quantized current blockade and hydrodynamic correlations in biopolymer translocation through nanopores: evidence from multiscale simulations

Massimo Bernaschi, Simone Melchionna, Sauro Succi, Maria Fyta, Efthimios Kaxiras

摘要:

我们提出了一个详细的描述,在溶剂的存在下,通过一个纳米孔的生物聚合物易位,使用创新的多尺度的方法,该方法将在微观尺度的生物聚合物与自洽的介观描述相结合的溶剂流体动力学。我们报告的证据量化电流封锁取决于折叠配置,并提供详细的信息,在加快易位过程中的流体动力学相关性的作用。

英文摘要:

We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent, using an innovative multi-scale methodology which treats the biopolymer at the microscopic scale as combined with a self-consistent mesoscopic description for the solvent fluid dynamics. We report evidence for quantized current blockade depending on the folding configuration and offer detailed information on the role of hydrodynamic correlations in speeding-up the translocation process.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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