生命科学家第一次接触统计力学
A First Exposure to Statistical Mechanics for Life Scientists
摘要：
统计力学是定量科学中最强大和最优雅的工具之一。统计力学的一个关键优点是，它旨在研究具有许多相互作用的自由度的大型系统，这提供了一个线索，即它可能与生命物质分子的分析有关。由于生物系统的数据变得越来越定量，因此随之而来的要求是，所提出的描述生物系统的模型本身是定量的。我们描述了如何统计力学是定量工具包，需要响应这些数据的一部分。统计力学的力量并不局限于传统的物理和化学问题，这些思想可以以许多有趣的方式应用于生物学。本文报告了我们的努力，教统计力学的生命科学专业的学生，并提供了一个框架，为其他有兴趣把这些工具，以非传统的观众在生命科学。
英文摘要：
Statistical mechanics is one of the most powerful and elegant tools in the quantitative sciences. One key virtue of statistical mechanics is that it is designed to examine large systems with many interacting degrees of freedom, providing a clue that it might have some bearing on the analysis of the molecules of living matter. As a result of data on biological systems becoming increasingly quantitative, there is a concomitant demand that the models set forth to describe biological systems be themselves quantitative. We describe how statistical mechanics is part of the quantitative toolkit that is needed to respond to such data. The power of statistical mechanics is not limited to traditional physical and chemical problems and there are a host of interesting ways in which these ideas can be applied in biology. This article reports on our efforts to teach statistical mechanics to life science students and provides a framework for others interested in bringing these tools to a nontraditional audience in the life sciences.
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