Nd:YAG laser介导γ-Fe2O3纳米粒子在大肠杆菌热疗中的应用
Applications of nanoparticles of gamma Fe2O3 for hyperthermia in E.coli by Nd:YAG laser
摘要:
本文探讨了使用γ-Fe 2 O3纳米粒子通过吸收Nd:YAG激光器发出的1064 nm辐射对生物体进行热疗。大肠杆菌细胞已经被用作用于证明其中赖氨酸被用作细胞壁和纳米颗粒之间的界面的效果的模型系统。扫描电子显微镜观察已经唯一地证明,氧化铁纳米颗粒与赖氨酸一起单独附着是吸收上述辐射的原因。通过细胞的生长速率测量和蛋白质评估提供了定量估计。采用直流电弧等离子体辅助气相凝聚法制备了γ-Fe 2 O3纳米粒子。
英文摘要:
The paper explores the use of nanoparticles of gamma Fe2O3 for hyperthermia treatment of living organisms by absorption of 1064 nm radiations from Nd:YAG laser. Escherichia coli cells have been used as the model system for demonstrating the effect wherein lysine is used as an interface between the cell walls and the nanoparticles. Scanning Electron Microscopic observations have, exclusively, proved that attachment of nanoparticles of iron oxide along with lysine alone is responsible for absorption of above radiations. The quantitative estimation has been provided by growth rate measurements and protein assessment of the cells. The nanoparticles of gamma Fe2O3 were synthesized by DC arc plasma assisted gas phase condensation.
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