生物进化的傅立叶分析：选择矩的概念
Fourier Analysis of Biological Evolution: Concept of Selection Moment
摘要：
许多蛋白质家族的二级结构元件在其相对面上表现出差异保守性。根据定义，两亲性螺旋和β-折叠具有这种性质，并发挥关键的功能作用。蛋白质家族的这种类型的进化轨迹通常对蛋白质家族的功能以及在亚家族内创建功能至关重要。也就是说，微分守恒保持了蛋白质结构与其方向相关的性质，这些性质在包装，识别和催化中很重要。在这里，我定义并制定了一个新的概念，称为选择时刻，检测这种进化过程中的蛋白质序列。它的各种应用程序的治疗是详细的。
英文摘要：
Secondary structure elements of many protein families exhibit differential conservation on their opposing faces. Amphipathic helices and beta-sheets by definition possess this property, and play crucial functional roles. This type of evolutionary trajectory of a protein family is usually critical to the functions of the protein family, as well as in creating functions within subfamilies. That is, differential conservation maintains properties of a protein structure related to its orientation, and that are important in packing, recognition, and catalysis. Here I define and formulate a new concept, called the selection moment, that detects this evolutionary process in protein sequences. A treatment of its various applications is detailed.
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