AROMA: Augmented Reasoning Over a Multimodal Architecture for Virtual Cell Genetic Perturbation Modeling
AROMA:增强的多模态架构下虚拟细胞基因扰动建模推理
机构 * AI for Life Sciences Lab, Tencent(腾讯AI生命科学实验室) ; Shenzhen International Graduate School, Tsinghua University(深圳国际研究生院,清华大学)
AI总结 AROMA通过整合文本证据、图拓扑信息和蛋白质序列特征,提升虚拟细胞基因扰动预测的准确性和可解释性,构建了包含498k样本的 PerturbReason 数据集,实验表明其在多个细胞系中表现优异。
Comments Accepted to ACL 2026 as a Findings paper. Zhenyu Wang and Geyan Ye are equal contributors; Geyan Ye is the corresponding author and project lead