Causal representation learning has attracted significant research interest during the past few years, as a means for improving model generalization and robustness. Causal representations of interventional image pairs (also called ``actionable counterfactuals'' in the literature), have the property that only variables corresponding to scene elements affected by the intervention / action are changed between the start state and the end state. While most work in this area has focused on identifying and representing the variables of the scene under a causal model, fewer efforts have focused on representations of the interventions themselves. In this work, we show that an effective strategy for improving out of distribution (OOD) robustness is to focus on the representation of actionable counterfactuals in the latent space. Specifically, we propose that an intervention can be represented by a Causal Delta Embedding that is invariant to the visual scene and sparse in terms of the causal variables it affects. Leveraging this insight, we propose a method for learning causal representations from image pairs, without any additional supervision. Experiments in the Causal Triplet challenge demonstrate that Causal Delta Embeddings are highly effective in OOD settings, significantly exceeding baseline performance in both synthetic and real-world benchmarks.

Automatically generating and iteratively editing academic slide decks requires more than document summarization. It demands faithful content selection, coherent slide organization, layout-aware rendering, and robust multi-turn instruction following. However, existing benchmarks and evaluation protocols do not adequately measure these challenges. To address this gap, we introduce the Deck Edits and Compliance Kit Benchmark (DECKBench), an evaluation framework for multi-agent slide generation and editing. DECKBench is built on a curated dataset of paper to slide pairs augmented with realistic, simulated editing instructions. Our evaluation protocol systematically assesses slide-level and deck-level fidelity, coherence, layout quality, and multi-turn instruction following. We further implement a modular multi-agent baseline system that decomposes the slide generation and editing task into paper parsing and summarization, slide planning, HTML creation, and iterative editing. Experimental results demonstrate that the proposed benchmark highlights strengths, exposes failure modes, and provides actionable insights for improving multi-agent slide generation and editing systems. Overall, this work establishes a standardized foundation for reproducible and comparable evaluation of academic presentation generation and editing. Code and data are publicly available at https://github.com/morgan-heisler/DeckBench .

Physical activity during hip fracture rehabilitation is essential for mitigating long-term functional decline in geriatric patients. However, it is rarely quantified in clinical practice. Existing continuous monitoring systems with commercially available wearable activity trackers are typically developed in middle-aged adults and therefore perform unreliably in older adults with slower and more variable gait patterns. This study aimed to develop a robust human activity recognition (HAR) system to improve continuous physical activity recognition in the context of hip fracture rehabilitation. 24 healthy older adults aged over 80 years were included to perform activities of daily living (walking, standing, sitting, lying down, and postural transfers) under simulated free-living conditions for 75 minutes while wearing two accelerometers positioned on the lower back and anterior upper thigh. Model robustness was evaluated using leave-one-subject-out cross-validation. The synthetic data demonstrated potential to improve generalization across participants. The resulting feature intervention model (FIM), aided by synthetic data guidance, achieved reliable activity recognition with mean F1-scores of 0.896 for walking, 0.927 for standing, 0.997 for sitting, 0.937 for lying down, and 0.816 for postural transfers. Compared with a control condition model without synthetic data, the FIM significantly improved the postural transfer detection, i.e., an activity class of high clinical relevance that is often overlooked in existing HAR literature. In conclusion, these preliminary results demonstrate the feasibility of robust activity recognition in older adults. Further validation in hip fracture patient populations is required to assess the clinical utility of the proposed monitoring system.

Feature space topology refers to the organization of samples within the feature space. Modifying this topology can be beneficial in machine learning applications, including dimensionality reduction, generative modeling, transfer learning, and robustness to adversarial attacks. This paper introduces a novel loss function, Hopkins loss, which leverages the Hopkins statistic to enforce a desired feature space topology, which is in contrast to existing topology-related methods that aim to preserve input feature topology. We evaluate the effectiveness of Hopkins loss on speech, text, and image data in two scenarios: classification and dimensionality reduction using nonlinear bottleneck autoencoders. Our experiments show that integrating Hopkins loss into classification or dimensionality reduction has only a small impact on classification performance while providing the benefit of modifying feature topology.

Computer-aided design (CAD) is vital to modern manufacturing, yet model creation remains labor-intensive and expertise-heavy. To enable non-experts to translate intuitive design intent into manufacturable artifacts, recent large language models-based text-to-CAD efforts focus on command sequences or script-based formats like CadQuery. However, these formats are kernel-dependent and lack universality for manufacturing. In contrast, the Standard for the Exchange of Product Data (STEP, ISO 10303) file is a widely adopted, neutral boundary representation (B-rep) format directly compatible with manufacturing, but its graph-structured, cross-referenced nature poses unique challenges for auto-regressive LLMs. To address this, we curate a dataset of ~40K STEP-caption pairs and introduce novel preprocessing tailored for the graph-structured format of STEP, including a depth-first search-based reserialization that linearizes cross-references while preserving locality and chain-of-thought(CoT)-style structural annotations that guide global coherence. We integrate retrieval-augmented generation to ground predictions in relevant examples for supervised fine-tuning, and refine generation quality through reinforcement learning with a specific Chamfer Distance-based geometric reward. Experiments demonstrate consistent gains of our STEP-LLM in geometric fidelity over the Text2CAD baseline, with improvements arising from multiple stages of our framework: the RAG module substantially enhances completeness and renderability, the DFS-based reserialization strengthens overall accuracy, and the RL further reduces geometric discrepancy. Both metrics and visual comparisons confirm that STEP-LLM generates shapes with higher fidelity than Text2CAD. These results show the feasibility of LLM-driven STEP model generation from natural language, showing its potential to democratize CAD design for manufacturing.

This study introduces KPoEM (Korean Poetry Emotion Mapping), a novel dataset that serves as a foundation for both emotion-centered analysis and generative applications in modern Korean poetry. Despite advancements in NLP, poetry remains underexplored due to its complex figurative language and cultural specificity. We constructed a multi-label dataset of 7,662 entries (7,007 line-level and 615 work-level), annotated with 44 fine-grained emotion categories from five influential Korean poets. The KPoEM emotion classification model, fine-tuned through a sequential strategy -- moving from general-purpose corpora to the specialized KPoEM dataset -- achieved an F1-micro score of 0.60, significantly outperforming previous models (0.43). The model demonstrates an enhanced ability to identify temporally and culturally specific emotional expressions while preserving core poetic sentiments. Furthermore, applying the structured emotion dataset to a RAG-based poetry generation model demonstrates the empirical feasibility of generating texts that reflect the emotional and cultural sensibilities of Korean literature. This integrated approach strengthens the connection between computational techniques and literary analysis, opening new pathways for quantitative emotion research and generative poetics. Overall, this study provides a foundation for advancing emotion-centered analysis and creation in modern Korean poetry.

Closed-loop control remains an open challenge in soft robotics. The nonlinear responses of soft actuators under dynamic loading conditions limit the use of analytic models for soft robot control. Traditional methods of controlling soft robots underutilize their configuration spaces to avoid nonlinearity, hysteresis, large deformations, and the risk of actuator damage. Furthermore, episodic data-driven control approaches such as reinforcement learning (RL) are traditionally limited by sample efficiency and inconsistency across initializations. In this work, we demonstrate RL for reliably learning control policies for dynamic balancing tasks in real-time single-shot hardware deployments. We use a deformable Stewart platform constructed using parallel, 3D-printed soft actuators based on motorized handed shearing auxetic (HSA) structures. By introducing a curriculum learning approach based on expanding neighborhoods of a known equilibrium, we achieve reliable single-deployment balancing at arbitrary coordinates. In addition to benchmarking the performance of model-based and model-free methods, we demonstrate that in a single deployment, Maximum Diffusion RL is capable of learning dynamic balancing after half of the actuators are effectively disabled, by inducing buckling and by breaking actuators with bolt cutters. Training occurs with no prior data, in as fast as 15 minutes, with performance nearly identical to the fully-intact platform. Single-shot learning on hardware facilitates soft robotic systems reliably learning in the real world and will enable more diverse and capable soft robots.

In this paper, we present the Residual Integral Solver Network (RISN), a novel neural network architecture designed to solve a wide range of integral and integro-differential equations, including one-dimensional, multi-dimensional, ordinary and partial integro-differential, systems, fractional types, and Helmholtz-type integral equations involving oscillatory kernels. RISN integrates residual connections with high-accuracy numerical methods such as Gaussian quadrature and fractional derivative operational matrices, enabling it to achieve higher accuracy and stability than traditional Physics-Informed Neural Networks (PINN). The residual connections help mitigate vanishing gradient issues, allowing RISN to handle deeper networks and more complex kernels, particularly in multi-dimensional problems. Through extensive experiments, we demonstrate that RISN consistently outperforms not only classical PINNs but also advanced variants such as Auxiliary PINN (A-PINN) and Self-Adaptive PINN (SA-PINN), achieving significantly lower Mean Absolute Errors (MAE) across various types of equations. These results highlight RISN's robustness and efficiency in solving challenging integral and integro-differential problems, making it a valuable tool for real-world applications where traditional methods often struggle.

Over-prompting, a phenomenon where excessive examples in prompts lead to diminished performance in Large Language Models (LLMs), challenges the conventional wisdom about in-context few-shot learning. To investigate this few-shot dilemma, we outline a prompting framework that leverages three standard few-shot selection methods - random sampling, semantic embedding, and TF-IDF vectors - and evaluate these methods across multiple LLMs, including GPT-4o, GPT-3.5-turbo, DeepSeek-V3, Gemma-3, LLaMA-3.1, LLaMA-3.2, and Mistral. Our experimental results reveal that incorporating excessive domain-specific examples into prompts can paradoxically degrade performance in certain LLMs, which contradicts the prior empirical conclusion that more relevant few-shot examples universally benefit LLMs. Given the trend of LLM-assisted software engineering and requirement analysis, we experiment with two real-world software requirement classification datasets. By gradually increasing the number of TF-IDF-selected and stratified few-shot examples, we identify their optimal quantity for each LLM. This combined approach achieves superior performance with fewer examples, avoiding the over-prompting problem, thus surpassing the state-of-the-art by 1% in classifying functional and non-functional requirements.

We introduce a novel symbolic regression framework, namely KAN-SR, built on Kolmogorov Arnold Networks (KANs) which follows a divide-and-conquer approach. Symbolic regression searches for mathematical equations that best fit a given dataset and is commonly solved with genetic programming approaches. We show that by using deep learning techniques, more specific KANs, and combining them with simplification strategies such as translational symmetries and separabilities, we are able to recover ground-truth equations of the Feynman Symbolic Regression for Scientific Discovery (SRSD) dataset. Additionally, we show that by combining the proposed framework with neural controlled differential equations, we are able to model the dynamics of an in-silico bioprocess system precisely, opening the door for the dynamic modeling of other engineering systems.

The advancement of autonomous robotic systems has led to impressive capabilities in perception, localization, mapping, and control. Yet, a fundamental gap remains: existing frameworks excel at geometric reasoning and dynamic stability but fall short in representing and preserving relational semantics, contextual reasoning, and cognitive transparency essential for collaboration in dynamic, human-centric environments. This paper introduces a unified architecture comprising the Ontology Neural Network (ONN) and the Ontological Real-Time Semantic Fabric (ORTSF) to address this gap. The ONN formalizes relational semantic reasoning as a dynamic topological process. By embedding Forman-Ricci curvature, persistent homology, and semantic tensor structures within a unified loss formulation, ONN ensures that relational integrity and topological coherence are preserved as scenes evolve over time. The ORTSF transforms reasoning traces into actionable control commands while compensating for system delays. It integrates predictive and delay-aware operators that ensure phase margin preservation and continuity of control signals, even under significant latency conditions. Empirical studies demonstrate the ONN + ORTSF framework's ability to unify semantic cognition and robust control, providing a mathematically principled and practically viable solution for cognitive robotics.

Federated Learning (FL) offers a privacy-preserving framework for training audio classification (AC) models across decentralized clients without sharing raw data. However, Federated Audio Classification (FedAC) faces three major challenges: data heterogeneity, model heterogeneity, and data poisoning, which degrade performance in real-world settings. While existing methods often address these issues separately, a unified and robust solution remains underexplored. We propose FedMLAC, a mutual learning-based FL framework that tackles all three challenges simultaneously. Each client maintains a personalized local AC model and a lightweight, globally shared Plug-in model. These models interact via bidirectional knowledge distillation, enabling global knowledge sharing while adapting to local data distributions, thus addressing both data and model heterogeneity. To counter data poisoning, we introduce a Layer-wise Pruning Aggregation (LPA) strategy that filters anomalous Plug-in updates based on parameter deviations during aggregation. Extensive experiments on four diverse audio classification benchmarks, including both speech and non-speech tasks, show that FedMLAC consistently outperforms state-of-the-art baselines in classification accuracy and robustness to noisy data.

Physical activity energy expenditure (PAEE) can be measured from breath-by-breath respiratory data, which can serve as a reference. Alternatively, PAEE can be predicted from the body movements, which can be measured and estimated with accelerometers. The body center of mass (COM) acceleration reflects the movements of the whole body and thus serves as a good predictor for PAEE. However, the wrist has also become a popular location due to recent advancements in wrist-worn devices. Therefore, in this work, using the respiratory data measured by COSMED K5 as the reference, we evaluated and compared the performances of COM-based settings and wrist-based settings. The COM-based settings include two different accelerometer compositions, using only the pelvis accelerometer (pelvis-acc) and the pelvis accelerometer with two accelerometers from two thighs (3-acc). The wrist-based settings include using only the left wrist accelerometer (l-wrist-acc) and only the right wrist accelerometer (r-wrist-acc). We implemented two existing PAEE estimation methods on our collected dataset, where 9 participants performed activities of daily living while wearing 5 accelerometers (i.e., pelvis, two thighs, and two wrists). These two methods include a linear regression (LR) model and a CNN-LSTM model. Both models yielded the best results with the COM-based 3-acc setting (LR: $R^2$ = 0.41, CNN-LSTM: $R^2$ = 0.53). No significant difference was found between the 3-acc and pelvis-acc settings (p-value = 0.278). For both models, neither the l-wrist-acc nor the r-wrist-acc settings demonstrated predictive power on PAEE with $R^2$ values close to 0, significantly outperformed by the two COM-based settings (p-values $<$ 0.05). No significant difference was found between the two wrists (p-value = 0.329).

Recent studies indicate that when faced with explicit biases in prompts, models often omit mentioning these biases in their Chain-of-Thought (CoT) output, revealing that verbalized reasoning can give an incorrect picture of how models arrive at conclusions (unfaithfulness). In this work, we show that unfaithful CoT also occurs on naturally worded, non-adversarial prompts without adding artificial biases or editing model outputs. We find that when separately presented with the questions "Is X bigger than Y?" and "Is Y bigger than X?", models sometimes produce superficially coherent arguments to justify systematically answering Yes to both or No to both, despite the contradiction. We present preliminary evidence that this is due to models' implicit biases towards Yes or No, labeling this Implicit Post-Hoc Rationalization. Our results reveal rates up to 13% for production models, and while frontier models are more faithful, none are entirely so, including thinking models like DeepSeek R1 (0.37%) and Sonnet 3.7 with thinking (0.04%). We also investigate Unfaithful Illogical Shortcuts, where models use subtly illogical reasoning to make speculative answers to hard math problems seem rigorously proven. Our findings indicate that while CoT can be useful for assessing outputs, it is not a complete account of the internal process that produced the model's answer and should be used with caution in agentic or safety-critical settings.

The recently-developed infant wearable MAIJU provides a means to automatically evaluate infants' motor performance in an objective and scalable manner in out-of-hospital settings. This information could be used for developmental research and to support clinical decision-making, such as detection of developmental problems and guiding of their therapeutic interventions. MAIJU-based analyses rely fully on the classification of infant's posture and movement; it is hence essential to study ways to increase the accuracy of such classifications, aiming to increase the reliability and robustness of the automated analysis. Here, we investigated how self-supervised pre-training improves performance of the classifiers used for analyzing MAIJU recordings, and we studied whether performance of the classifier models is affected by context-selective quality-screening of pre-training data to exclude periods of little infant movement or with missing sensors. Our experiments show that i) pre-training the classifier with unlabeled data leads to a robust accuracy increase of subsequent classification models, and ii) selecting context-relevant pre-training data leads to substantial further improvements in the classifier performance.

When domain experts are needed to perform data annotation for complex machine-learning tasks, reducing annotation effort is crucial in order to cut down time and expenses. For cases when there are no annotations available, one approach is to utilize the structure of the feature space for clustering-based active learning (AL) methods. However, these methods are heavily dependent on how the samples are organized in the feature space and what distance metric is used. Unsupervised methods such as contrastive predictive coding (CPC) can potentially be used to learn organized feature spaces, but these methods typically create high-dimensional features which might be challenging for estimating data density. In this paper, we combine CPC and multiple dimensionality reduction methods in search of functioning practices for clustering-based AL. Our experiments for simulating speech emotion recognition system deployment show that both the local and global topology of the feature space can be successfully used for AL, and that CPC can be used to improve clustering-based AL performance over traditional signal features. Additionally, we observe that compressing data dimensionality does not harm AL performance substantially, and that 2-D feature representations achieved similar AL performance as higher-dimensional representations when the number of annotations is not very low.

Dementia and depression are the most prevalent neuropsychiatric disorders in geriatric populations, and their overlapping symptoms pose major challenges for differential diagnosis. In this study, we investigate open-weights Large Language Models (LLMs) for predicting dementia and depression severity from speech samples collected during standardized history taking interviews with 154 German-speaking subjects. We introduce an observer-based Global Depression Scale (GDS-D) aligned with the established Global Deterioration Scale (GDS), enabling parallel global staging of affective and cognitive symptoms. We compare three LLMs (Mistral 3.1, DeepHermes, Qwen3) in two settings: (1) zero-shot prediction and (2) LLM-based feature extraction for Support Vector Regression, using human and pause-enriched transcripts. Results show that LLMs effectively predict depression severity in zero-shot settings (best MAE of 0.60), while dementia assessment benefits substantially from structured feature extraction (best MAE of 0.78), reducing errors by up to 35% over zero-shot baselines. Pause-enriched transcripts achieve competitive performance with human transcriptions, demonstrating the viability of fully automatic screening pipelines for differential neuropsychiatric assessment.

Constraint-based causal discovery relies on repeated conditional independence tests, but fast nonparametric tests often sacrifice calibration, especially when variables depend on the conditioning set through nonlinear relationships. We introduce BLITZ (Broad-to-Local Independence Testing via residualiZation), a nonparametric conditional independence test designed to run well under a second while maintaining the accuracy needed for the thousands of queries performed by constraint-based causal discovery algorithms. BLITZ first removes broad smooth dependence on the conditioning set using low-order polynomial regression, then applies a small nonlinear feature map and residualizes those features with shallow tree regressions. The resulting statistic tests residual cross-covariance, with a moment-matched chi-square approximation to the null distribution. We show theoretically that the two-stage design reduces the effective complexity faced by the tree residualizers, allowing shallow trees to control residual conditional-mean bias while avoiding excessive overfitting. In simulations, BLITZ provides better null calibration than fast kernel, random-feature, and regression-based competitors while remaining among the fastest methods tested. In causal discovery experiments on synthetic graphs and flow-cytometry data, BLITZ yields more reliable endpoint orientations among retained adjacencies and competitive structural recovery. These results suggest that broad-to-local residualization is a practical route to calibrated, scalable nonparametric conditional independence testing for causal discovery.

We study the privacy of releasing posterior sample paths from a Gaussian process (GP) when the entire training set including covariates and responses is private. Unlike standard differential-privacy (DP) mechanisms that add external noise, posterior sampling is random by construction. We show that this intrinsic randomness yields DP guarantees by deriving explicit Rényi-DP bounds for GP posterior sample-path release. The bounds separate posterior-mean leakage from data-dependent posterior-covariance leakage showing that meaningful privacy depends sharply on effective ridge regularisation. We apply membership-inference attacks to show that empirical leakage follows the predicted dependence on regularisation, posterior variance and the number of released posterior sample-paths. Utility experiments on downstream posterior-sampling tasks identify noisy-observation regimes where privacy-compatible regularisation preserves useful decisions with modest utility loss. When stronger privacy is needed, the intrinsic guarantee can be sharpened by adding calibrated GP noise, providing an explicit additional privacy knob.

Graph-based learning methods have become increasingly prominent due to their strong performance across diverse applications. Among these, recent frameworks grounded in diffusion processes provide a unifying perspective that extends traditional graph neural network formulations while addressing limitations of standard message-passing mechanisms. Despite these advances, concerns remain regarding the fairness of such models, as they may propagate or amplify biases present in the data. In this work, we introduce a fairness-aware adaptation of graph-based diffusion by modifying the underlying Laplacian operator. Our approach incorporates multiple complementary transformations, including subspace projections, spectral adjustments, and frequency-based filtering, to mitigate bias-related components. Leveraging the intrinsic smoothing properties of graph diffusion, we provide a principled analysis of the resulting behavior and establish theoretical insights into fairness properties. We evaluate the proposed framework on both synthetic and real-world datasets, demonstrating that it achieves competitive performance while improving fairness metrics with limited additional computational cost.

Non-autoregressive (NAR) decoding generates output tokens in parallel, making speech recognition faster than autoregressive decoding, which generates them sequentially from left to right. However, the recognition performance is degraded because NAR decoding cannot resolve uncertainty by conditioning on previously generated tokens. To address this issue, we propose a novel NAR decoding framework based on minimum Bayes' risk (MBR) decoding, termed NAR-MBR decoding, that maximizes the expected utility calculated from samples drawn from the output probability of an NAR model rather than maximizing the output probability. Notably, by leveraging the nature of NAR models, multiple samples are obtained efficiently with a single forward computation. Our experiments across LibriSpeech, Switchboard, AMI, and web presentation corpus demonstrated that our NAR-MBR decoding outperformed previous NAR decoding and ran faster than AR decoding.

Binary data factorization is common, but real-valued methods ignore discreteness and yield hard-to-interpret factors. Boolean Matrix Factorization (BooMF) instead decomposes a binary matrix into two lower-rank binary matrices via logical AND and OR, expressing the data as a Boolean disjunction of interpretable patterns. In cancer genomics, BooMF can reveal coordinated feature changes that may drive tumor evolution, unlike rotational or additive decompositions. Most existing BooMF methods are heuristic, greedy, sensitive to initialization, prone to local optima, and do not support principled model selection or uncertainty quantification. We introduce Bayesian Boolean Matrix Factorization (BBMF), a fully conjugate generative model with sparsity-inducing priors. It enforces Boolean constraints, yields interpretable latent factors with coherent uncertainty quantification, and admits Gibbs sampling with closed-form full conditionals. Because cancer evolution often involves widespread, near-simultaneous chromosome-number changes (e.g., whole-genome duplication followed by instability and selection), Boolean factorizations capture these patterns more naturally than additive models. Applied to arm-level copy-number alteration data in multiple myeloma, where entries indicate presence/absence of chromosomal-arm amplifications, BBMF finds a small set of interpretable bicliques linking patient subsets to recurrently co-altered chromosomal arms, providing a compact, biologically meaningful summary of tumor heterogeneity and demonstrating BBMF's utility for uncovering discrete latent structure in complex binary data.

Tau PET imaging is central to tracking Alzheimer's disease progression, but systematic differences between scanners, protocols, and radiotracers across sites introduce nonbiological variability that inflates biomarker variance, reduces sensitivity to disease effects, and can bias downstream clinical assessments. Harmonization methods aim to remove these site-induced shifts while preserving biologically meaningful signal, yet existing approaches struggle when source and target cohorts differ in subgroup composition, risking conflation of site effects with biological variation such as tau-positivity status. We propose the Feynman Kac Reweighted Schröodinger Bridge Matching (FKRSBM) model to address this problem. Rather than routing data through a Gaussian noise prior as in diffusion-based methods, FKRSBM learns a direct stochastic transport process between source and target distributions via entropy-regularized optimal transport. To enforce biologically consistent transport, FKRSBM incorporates a subgroup-aware endpoint proposal derived from a Feynman Kac reweighting of the reference bridge measure, implemented entirely through stratified importance sampling at the data level and requiring no changes to the underlying bridge-matching solver or network architecture. For surface-based neuroimaging, FKRSBM employs a spherical convolutional backbone operating on cortical meshes to perform vertex-level harmonization. We evaluate the method on tau PET SUVR maps, harmonizing PI-2620 data from the HABS-HD cohort into the AV-1451 domain of ADNI. Compared against ComBat, CycleGAN, a diffusion-based method (DF), and unregularized Diffusion Schröodinger Bridge Matching (DSBM), FKRSBM achieves superior distributional alignment, reduced tau-positivity sign mismatch, stronger APOE subgroup alignment, and improved downstream disease classification performance.

Text-to-audio (TTA) generation, synthesizing audio from natural language, has been widely studied for its ability to capture precise user intent. To effectively advance TTA models, it is essential to reliably evaluate generated audio without relying on costly human subjective ratings, motivating the development of automatic evaluation metrics that correlate well with human judgments. While recent CLAP-based metrics provide practical reference-free solutions, their coarse-grained text-audio similarity matching often correlates poorly with human ratings. To address this, we propose ELSA, a reference-free evaluation metric for fine-grained text-audio alignment. ELSA decomposes generated audio guided by distinct acoustic events derived from the text query and assesses event-level alignment. Experiments across four TTA benchmarks show that ELSA reveals a higher correlation with human subjective ratings than prior metrics, highlighting its effectiveness for reliable TTA evaluation.

Agentic artificial intelligence systems introduce a new class of model risk. Unlike traditional predictive models, autonomous agents continuously acquire information, form beliefs regarding latent states of the environment, generate forecasts, select actions, and adapt their behavior over time. Existing validation methodologies focus primarily on predictive accuracy and therefore provide limited insight into the quality of the underlying decision process. This paper proposes a model validation framework for agentic AI based on Partially Observable Markov Decision Processes (POMDPs). The framework decomposes autonomous decision making into information, beliefs, forecasts, actions, and utility, allowing each component to be validated independently. Large language models (LLMs) are formalized as approximate Bayesian filtering operators, and a model-risk taxonomy is developed encompassing state-space, filtering, forecast, policy, utility-specification, and parameter risks. The model risk validation methodology is demonstrated through a portfolio-management case study in which an agent infers latent market regimes from market and macroeconomic information, generates belief-conditioned forecasts, and constructs portfolios using a Black--Litterman framework. Empirical validation combines performance analysis, belief calibration diagnostics, coverage tests, ablation studies, and parameter-sensitivity analysis. The results indicate that latent-state inference contributes independently to decision quality and that the principal conclusions remain robust across a broad range of parameter values. The principal contribution of the paper is a practical framework for extending established model risk management concepts to autonomous AI systems and providing a rigorous foundation for their validation, governance, and monitoring.

The full potential of artificial intelligence in tibial plateau fracture characterisation remains unrealised, constrained by a fundamental dependency on labelled datasets whose consistency cannot be guaranteed: conventional classification schemes such as Schatzker and AO/OTA suffer from inter-observer variability, causing supervised models to learn human disagreement rather than stable fracture morphology. We design, implement, and validate a label-agnostic framework that eliminates this constraint by learning fracture representations directly from imaging data without observer-assigned labels. A RadImageNet-pretrained ResNet-50 encoder is fine-tuned on 154 cleaned knee radiographs using the SimCLR contrastive objective, preceded by a data cleaning protocol and followed by UMAP dimensionality reduction and k-means clustering to discover four imaging-derived phenotypes. Phenotype validity is assessed through a blinded expert review protocol administered to two independent clinicians. The four phenotypes demonstrate robust stability (bootstrap ARI = 0.319 +/- 0.041), strong internal cohesion (silhouette = 0.511), and coherence ratings of 3-5/5 from both reviewers under blinded conditions; one phenotype was unanimously identified as exhibiting comminution -- a high-complexity feature isolated without any supervisory signal. Inter-partition comparison against Schatzker labels yields ARI = 0.013, confirming orthogonality to conventional classification boundaries. Notably, expert reviewers anchored to established classification vocabularies perceived imaging-derived groups as heterogeneous precisely where Schatzker alignment was lowest, suggesting that Schatzker-trained perception and label-agnostic embedding geometry measure orthogonal dimensions. These findings establish label-agnostic SSL phenotyping as a reproducible and clinically interpretable complement to conventional classification.

It is well known that intelligibility of speech reduces in the presence of ambient noise. However, studies show that all sounds are not affected uniformly (or equally) and that vowels are more robust to noise than consonants. In this study, intelligibility of various consonants is assessed and analyzed in stationary white noise and non-stationary babble noise conditions. Specifically, this study investigates the individual contribution of magnitude and phase spectra of a given speech signal on human speech recognition of consonants in noisy conditions. In this regard, three experiments are carried out. In experiment 1, clean signal, signal reconstructed with only magnitude spectrum information (magnitude only signal) and signal reconstructed with only phase spectrum information (phase only signal) are assessed for intelligibility. In experiment 2, noise is added to clean speech. From noisy speech, phase only signal and magnitude only signal are reconstructed and intelligibility tests are performed for all these three signals. In experiment 3, noise is added directly to the magnitude only and phase only signals reconstructed from clean speech and their intelligibility is assessed. Results of these experiments show that magnitude spectrum contributes more to intelligibility in clean condition than phase spectrum, while information from phase spectrum is more robust in noisy conditions. It is also observed that, among consonants, nasals are more susceptible to noise whereas fricatives and approximants were observed to be comparatively more robust.

This paper is concerned with learning principal variations of random probability measures on $\mathbb{R}^m$ under the Wasserstein geometry. We introduce a new dynamical formulation to interpret the log-PCA, a linearized principal geodesic analysis, as a variational approach. Our differentiable version, termed as the Wasserstein Tangential PCA (WT-PCA), captures the local principal modes of geodesic variations of a (weighted) probability measure on the Wasserstein space via its covariance operator at barycenter. Based on the dynamical perspective and leveraging parallel transport structure of the optimal transport problems, we derive a general statistical convergence rate of the empirical WT-PCA when estimated from data in terms of the 2-Wasserstein distance between the population and empirical barycenter reference measures.

Antimicrobial resistance causes to over a million deaths annually. Antimicrobial peptides (AMPs) are a promising solution, but generative AMP models are not yet ready to design peptides with non-natural amino acids and/or chemical modifications, which are essential for real-world peptide drugs. We present AMPGAN v3, a multi-objective conditional GAN that expands the generative vocabulary to D-amino acids and N/C-terminus modifications such as amidation. By separating adversarial and activity-aware supervision across two specialized discriminators, AMPGAN v3 substantially improves training stability and outperforms prior generative AMP models on external classifiers. We validated five candidates spanning three structural classes in vitro; two showed activity against Gram-positive strains, with the best candidate reaching MIC 8 μg/mL against B. subtilis. To support downstream curation, we further present PepCraft, a multi-agent framework for end-to-end AMP discovery in which a Planning Agent orchestrates specialized executors for generation, filtering, and verification. Its prioritization recommendations align with our in vitro outcomes. Together, these contributions let us examine, on a small but real scale, how generative and agentic AI compose in therapeutic peptide discovery. Code: https://github.com/marszzibros/AMPGANv3

Modern option-learning systems operate in two coordinates: price space, where markets quote and no-arbitrage constraints are most naturally enforced, and implied volatility (IV) space, where volatility surfaces are smoothed, regularized, and evaluated. The bottleneck is interface, not approximation: Jäckel's seminal "Let's Be Rational" (LBR) solver already inverts the Black-Scholes price to machine precision efficiently. What is missing is a differentiable layer that preserves LBR in the forward pass and avoids backpropagating through its branch logic. Such a layer must also confront the unavoidable singularity of the inverse map in the low-vega regime, where the sensitivity 1/vega diverges as vega -> 0. We close this gap with PIVOT, the Price-Implied-Volatility Objective Translator. PIVOT keeps the LBR forward pass intact and supplies the backward pass by implicit differentiation through the smooth Black-Scholes/Black-76 price map, with an explicit gating contract: invalid domains return NaN, well-conditioned rows receive the exact 1/vega gradient, and low-vega rows are attenuated rather than silently regularized. On a single H100, a fused Triton kernel reaches 1.79e9 IV/s at machine precision (9.3e-14 max relative error vs. the reference C solver); end-to-end label generation sustains 48.9M/s on synthetic chains and 16.6M/s on SPX OptionMetrics. In a HyperIV-style one-day reproduction on SPX, PIVOT-augmented objectives Pareto-dominate the baselines, reducing held-out price MAE by up to 43.4% and the strongest three-seed gated objective improving price MAE by 38.8% and IV MAE by 21.3% jointly; cross-asset results on RUT, VIX, and NDX show directional price-MAE gains of 40.1%, 24.2%, and 16.7%, while an ungated IV-roundtrip control collapses to a degenerate near-zero surface, confirming the gate as a correctness contract rather than a tuning knob.