Sign-language datasets are difficult to preprocess consistently because they vary in annotation schema, clip timing, signer framing, and privacy constraints. Existing work usually reports downstream models, while the preprocessing pipeline that converts raw video into training-ready pose or video artifacts remains fragmented, backend-specific, and weakly documented. We present SignDATA, a config-driven preprocessing toolkit that standardizes heterogeneous sign-language corpora into comparable outputs for learning. The system supports two end-to-end recipes: a pose recipe that performs acquisition, manifesting, person localization, clipping, cropping, landmark extraction, normalization, and WebDataset export, and a video recipe that replaces pose extraction with signer-cropped video packaging. SignDATA exposes interchangeable MediaPipe and MMPose backends behind a common interface, typed job schemas, experiment-level overrides, and per-stage checkpointing with config- and manifest-aware hashes. We validate the toolkit through a research-oriented evaluation design centered on backend comparison, preprocessing ablations, and privacy-aware video generation on datasets. Our contribution is a reproducible preprocessing layer for sign-language research that makes extractor choice, normalization policy, and privacy tradeoffs explicit, configurable, and empirically comparable.Code is available at https://github.com/balaboom123/signdata-slt.

Text-to-Image generation has seen significant advancements in output realism with the advent of diffusion models. However, diffusion models encounter difficulties when tasked with generating multiple objects, frequently resulting in hallucinations where certain entities are omitted. While existing solutions typically focus on optimizing latent representations within diffusion models, the relevance of the initial generation seed is typically underestimated. While using various seeds in multiple iterations can improve results, this method also significantly increases time and energy costs. To address this challenge, we introduce HEaD+ (Hallucination Early Detection +), a novel approach designed to identify incorrect generations early in the diffusion process. The HEaD+ framework integrates cross-attention maps and textual information with a novel input, the Predicted Final Image. The objective is to assess whether to proceed with the current generation or restart it with a different seed, thereby exploring multiple-generation seeds while conserving time. HEaD+ is trained on the newly created InsideGen dataset of 45,000 generated images, each containing prompts with up to seven objects. Our findings demonstrate a 6-8% increase in the likelihood of achieving a complete generation (i.e., an image accurately representing all specified subjects) with four objects when applying HEaD+ alongside existing models. Additionally, HEaD+ reduces generation times by up to 32% when aiming for a complete image, enhancing the efficiency of generating complete and accurate object representations relative to leading models. Moreover, we propose an integrated localization module that predicts object centroid positions and verifies pairwise spatial relations (if requested by the users) at an intermediate timestep, gating generation together with object presence to further improve relation-consistent outcomes.

Despite significant progress in Multi-modal Large Language Models (MLLMs), their clinical reasoning capacity for multi-modal diagnosis remains largely unexamined. Current benchmarks, mostly single-modality data, can't evaluate progressive reasoning and cross-modal integration essential for clinical practice. We introduce the Cross-Modality Progressive Clinical Reasoning (X-PCR) benchmark, the first comprehensive evaluation of MLLMs through a complete ophthalmology diagnostic workflow, with two reasoning tasks: 1) a six-stage progressive reasoning chain spanning image quality assessment to clinical decision-making, and 2) a cross-modality reasoning task integrating six imaging modalities. The benchmark comprises 26,415 images and 177,868 expert-verified VQA pairs curated from 51 public datasets, covering 52 ophthalmic diseases. Evaluation of 21 MLLMs reveals critical gaps in progressive reasoning and cross-modal integration. Dataset and code: https://github.com/CVI-SZU/X-PCR.

Ultrasound (US)-guided needle insertion is a critical yet challenging procedure due to dynamic imaging conditions and difficulties in needle visualization. Many methods have been proposed for automated needle insertion, but they often rely on hand-crafted pipelines with modular controllers, whose performance degrades in challenging cases. In this paper, a Vision-Language-Action (VLA) model is proposed for adaptive and automated US-guided needle insertion and tracking on a robotic ultrasound (RUS) system. This framework provides a unified approach to needle tracking and needle insertion control, enabling real-time, dynamically adaptive adjustment of insertion based on the obtained needle position and environment awareness. To achieve real-time and end-to-end tracking, a Cross-Depth Fusion (CDF) tracking head is proposed, integrating shallow positional and deep semantic features from the large-scale vision backbone. To adapt the pretrained vision backbone for tracking tasks, a Tracking-Conditioning (TraCon) register is introduced for parameter-efficient feature conditioning. After needle tracking, an uncertainty-aware control policy and an asynchronous VLA pipeline are presented for adaptive needle insertion control, ensuring timely decision-making for improved safety and outcomes. Extensive experiments on both needle tracking and insertion show that our method consistently outperforms state-of-the-art trackers and manual operation, achieving higher tracking accuracy, improved insertion success rates, and reduced procedure time, highlighting promising directions for RUS-based intelligent intervention.

Co-manipulation requires multiple humans to synchronize their motions with a shared object while ensuring reasonable interactions, maintaining natural poses, and preserving stable states. However, most existing motion generation approaches are designed for single-character scenarios or fail to account for payload-induced dynamics. In this work, we propose a flow-matching framework that ensures the generated co-manipulation motions align with the intended goals while maintaining naturalness and effectiveness. Specifically, we first introduce a generative model that derives explicit manipulation strategies from the object's affordance and spatial configuration, which guide the motion flow toward successful manipulation. To improve motion quality, we then design an adversarial interaction prior that promotes natural individual poses and realistic inter-person interactions during co-manipulation. In addition, we also incorporate a stability-driven simulation into the flow matching process, which refines unstable interaction states through sampling-based optimization and directly adjusts the vector field regression to promote more effective manipulation. The experimental results demonstrate that our method achieves higher contact accuracy, lower penetration, and better distributional fidelity compared to state-of-the-art human-object interaction baselines. The code is available at https://github.com/boycehbz/StaCOM.

Chain-of-Thought (CoT) reasoning significantly elevates the complex problem-solving capabilities of multimodal large language models (MLLMs). However, adapting CoT to vision typically discretizes signals to fit LLM inputs, causing early semantic collapse and discarding fine-grained details. While external tools can mitigate this, they introduce a rigid bottleneck, confining reasoning to predefined operations. Although recent latent reasoning paradigms internalize visual states to overcome these limitations, optimizing the resulting hybrid discrete-continuous action space remains challenging. In this work, we propose HyLaR (Hybrid Latent Reasoning), a framework that seamlessly interleaves discrete text generation with continuous visual latent representations. Specifically, following an initial cold-start supervised fine-tuning (SFT), we introduce DePO (Decoupled Policy Optimization) to enable effective reinforcement learning within this hybrid space. DePO decomposes the policy gradient objective, applying independent trust-region constraints to the textual and latent components, alongside an exact closed-form von Mises-Fisher (vMF) KL regularizer. Extensive experiments demonstrate that HyLaR outperforms standard MLLMs and state-of-the-art latent reasoning approaches across fine-grained perception and general multimodal understanding benchmarks. Code is available at https://github.com/EthenCheng/HyLaR.

Fine-grained spatiotemporal reasoning on surgical videos is critical, yet the capabilities of Multi-modal Large Language Models (MLLMs) in this domain remain largely unexplored. To bridge this gap, we introduce SurgCoT, a unified benchmark for evaluating chain-of-thought (CoT) reasoning in MLLMs across 7 surgical specialties and 35 diverse procedures. SurgCoT assesses five core reasoning dimensions: Causal Action Ordering, Cue-Action Alignment, Affordance Mapping, Micro-Transition Localization, and Anomaly Onset Tracking, through a structured CoT framework with an intensive annotation protocol (Question-Option-Knowledge-Clue-Answer), where the Knowledge field provides essential background context and Clue provides definitive spatiotemporal evidence. Evaluation of 10 leading MLLMs shows: 1) commercial models outperform open-source and medical-specialized variants; 2) significant gaps exist in surgical CoT reasoning; 3) SurgCoT enables effective evaluation and enhances progressive spatiotemporal reasoning. SurgCoT provides a reproducible testbed to narrow the gap between MLLM capabilities and clinical reasoning demands. Code: https://github.com/CVI-SZU/SurgCoT.

Composed image retrieval, multi-turn composed image retrieval, and composed video retrieval all share a common paradigm: composing the reference visual with modification text to retrieve the desired target. Despite this shared structure, the three tasks have been studied in isolation, with no prior work proposing a unified framework, let alone a zero-shot solution. In this paper, we propose UniCVR, the first unified zero-shot composed visual retrieval framework that jointly addresses all three tasks without any task-specific human-annotated data. UniCVR strategically combines two complementary strengths: Multimodal Large Language Models (MLLMs) for compositional query understanding and Vision-Language Pre-trained (VLP) models for structured visual retrieval. Concretely, UniCVR operates in two stages. In Stage I, we train the MLLM as a compositional query embedder via contrastive learning on a curated multi-source dataset of approximately 3.5M samples, bridging the heterogeneous embedding spaces between the MLLM and the frozen VLP gallery encoder. A cluster-based hard negative sampling strategy is proposed to strengthen contrastive supervision. In Stage II, we introduce an MLLM-guided dual-level reranking mechanism that applies adaptive budgeted subset scoring to a small number of top-ranked candidates, and then exploits the resulting relevance signals through a dual-level re-scoring scheme, producing more accurate final rankings with minimal computational overhead. Extensive experiments across five benchmarks covering all three tasks demonstrate that UniCVR achieves cutting-edge performance, validating its effectiveness and generalizability. Our data and code will be released upon acceptance.

GAN-based facial attribute editing is widely used in virtual avatars and social media but often suffers from attribute entanglement, where modifying one face attribute unintentionally alters others. While supervised disentangled representation learning can address this, it relies heavily on labeled data, incurring high annotation costs. To address these challenges, we propose MD-Face, a label-free disentangled representation learning framework based on Mixture of Experts (MoE). MD-Face utilizes a MoE backbone with a gating mechanism that dynamically allocates experts, enabling the model to learn semantic vectors with greater independence. To further enhance attribute entanglement, we introduce a geometry-aware loss, which aligns each semantic vector with its corresponding Semantic Boundary Vector (SBV) through a Jacobian-based pushforward method. Experiments with ProGAN and StyleGAN show that MD-Face outperforms unsupervised baselines and competes with supervised ones. Compared to diffusion-based methods, it offers better image quality and lower inference latency, making it ideal for interactive editing.

This technical note provides a first-order formalisation of the logit shift and fact-margin change induced by Low-Rank Adaptation (LoRA). Using a first-order Fréchet approximation around the base model trajectory, we show that the multi-layer LoRA effect can be decomposed into a linear summation of layerwise contributions and a higher-order remainder term representing inter-layer coupling.

In this paper, a deep learning framework is proposed for automatic facial emotion based on deep convolutional networks. In order to increase the generalization ability and the robustness of the method, the dataset size is increased by merging three publicly available facial emotion datasets: CK+, FER+ and KDEF. Despite the increase in dataset size, the minority classes still suffer from insufficient number of training samples, leading to data imbalance. The data imbalance problem is minimized by online and offline augmentation techniques and random weighted sampling. Experimental results demonstrate that the proposed method can recognize the seven basic emotions with 82% accuracy. The results demonstrate the effectiveness of the proposed approach in tackling the challenges of data imbalance and improving classification performance in facial emotion recognition.

Medical Visual Question Answering (MedVQA) aims to generate clinically reliable answers conditioned on complex medical images and questions. However, existing methods often overfit to superficial cross-modal correlations, neglecting the intrinsic biases embedded in multimodal medical data. Consequently, models become vulnerable to cross-modal confounding effects, severely hindering their ability to provide trustworthy diagnostic reasoning. To address this limitation, we propose a novel Dual Causal Inference (DCI) framework for MedVQA. To the best of our knowledge, DCI is the first unified architecture that integrates Backdoor Adjustment (BDA) and Instrumental Variable (IV) learning to jointly tackle both observable and unobserved confounders. Specifically, we formulate a Structural Causal Model (SCM) where observable cross-modal biases (e.g., frequent visual and textual co-occurrences) are mitigated via BDA, while unobserved confounders are compensated using an IV learned from a shared latent space. To guarantee the validity of the IV, we design mutual information constraints that maximize its dependence on the fused multimodal representations while minimizing its associations with the unobserved confounders and target answers. Through this dual mechanism, DCI extracts deconfounded representations that capture genuine causal relationships. Extensive experiments on four benchmark datasets, SLAKE, SLAKE-CP, VQA-RAD, and PathVQA, demonstrate that our method consistently outperforms existing approaches, particularly in out-of-distribution (OOD) generalization. Furthermore, qualitative analyses confirm that DCI significantly enhances the interpretability and robustness of cross-modal reasoning by explicitly disentangling true causal effects from spurious cross-modal shortcuts.

Realizing active visual tracking with a single unified model across diverse robots is challenging, as the physical constraints and motion dynamics vary drastically from one platform to another. Existing approaches typically train separate models for each embodiment, leading to poor scalability and limited generalization. To address this, we propose AdaTracker, an adaptive in-context policy learning framework that robustly tracks targets on diverse robot morphologies. Our key insight is to explicitly model embodiment-specific constraints through an Embodiment Context Encoder, which infers embodiment-specific constraints from history. This contextual representation dynamically modulates a Context-Aware Policy, enabling it to infer optimal control actions for unseen embodiments in a zero-shot manner. To enhance robustness, we introduce two auxiliary objectives to ensure accurate context identification and temporal consistency. Experiments in both simulation and the real world demonstrate that AdaTracker significantly outperforms state-of-the-art methods in cross-embodiment generalization, sample efficiency, and zero-shot adaptation.

Tactile sensors are increasingly integrated into dexterous robotic manipulators to enhance contact perception. However, learning manipulation policies that rely on tactile sensing remains challenging, primarily due to the trade-off between fidelity and computational cost of soft-body simulations. To address this, we present ETac, a tactile simulation framework that models elastomeric soft-body interactions with both high fidelity and efficiency. ETac employs a lightweight data-driven deformation propagation model to capture soft-body contact dynamics, achieving high simulation quality and boosting efficiency that enables large-scale policy training. When serving as the simulation backend, ETac produces surface deformation estimates comparable to FEM and demonstrates applicability for modeling real tactile sensors. Then, we showcase its capability in training a blind grasping policy that leverages large-area tactile feedback to manipulate diverse objects. Running on a single RTX 4090 GPU, ETac supports reinforcement learning across 4,096 parallel environments, achieving a total throughput of 869 FPS. The resulting policy reaches an average success rate of 84.45% across four object types, underscoring ETac's potential to make tactile-based skill learning both efficient and scalable.

Efficient single-image super-resolution (SISR) requires balancing reconstruction fidelity, model compactness, and robustness under low-bit deployment, which is especially challenging for x3 SR. We present a deployment-oriented quantized SISR framework based on an extract-refine-upsample design. The student performs most computation in the low-resolution space and uses a lightweight re-parameterizable backbone with PixelShuffle reconstruction, yielding a compact inference graph. To improve quality without significantly increasing complexity, we adopt a three-stage training pipeline: Stage 1 learns a basic reconstruction mapping with spatial supervision; Stage 2 refines fidelity using Charbonnier loss, DCT-domain supervision, and confidence-weighted output-level distillation from a Mamba-based teacher; and Stage 3 applies quantization-aware training directly on the fused deploy graph. We further use weight clipping and BatchNorm recalibration to improve quantization stability. On the MAI 2026 Quantized 4K Image Super-Resolution Challenge test set, our final AIO MAI submission achieves 29.79 dB PSNR and 0.8634 SSIM, obtaining a final score of 1.8 under the target mobile INT8 deployment setting. Ablation on Stage 3 optimization shows that teacher-guided supervision improves the dynamic INT8 TFLite reconstruction from 29.91 dB/0.853 to 30.0003 dB/0.856, while the fixed-shape deployable INT8 TFLite artifact attains 30.006 dB/0.857.

To enable autonomous wind estimation for energy-efficient flight in small unmanned aerial vehicles (UAVs), this study proposes a method that estimates flight states and wind using only the low-cost essential onboard sensors required for autonomous flight, without relying on additional wind measurement devices. The core of the method includes an Extended Kalman Filter (EKF) integrated with the aerodynamic model and an Adaptive Moving Average Estimation (AMAE) technique, which improves the accuracy and smoothness of the wind estimation. Simulation results show that the approach efficiently estimates both steady and time-varying 3D wind vectors without requiring flow angle measurements. The impact of aerodynamic model accuracy on wind estimation errors is also analyzed to assess practical applicability. Flight tests validate the effectiveness of the method and its feasibility for real-time onboard computation. Additionally, uncertainties and error sources encountered during testing are systematically examined, providing a foundation for further refinement.

Real-time world simulation is becoming a key infrastructure for scalable evaluation and online reinforcement learning of autonomous driving systems. Recent driving world models built on autoregressive video diffusion achieve high-fidelity, controllable multi-camera generation, but their inference cost remains a bottleneck for interactive deployment. However, existing diffusion caching methods are designed for offline video generation with multiple denoising steps, and do not transfer to this scenario. Few-step distilled models have no inter-step redundancy left for these methods to reuse, and sequence-level parallelization techniques require future conditioning that closed-loop interactive generation does not provide. We present X-Cache, a training-free acceleration method that caches along a different axis: across consecutive generation chunks rather than across denoising steps. X-Cache maintains per-block residual caches that persist across chunks, and applies a dual-metric gating mechanism over a structure- and action-aware block-input fingerprint to independently decide whether each block should recompute or reuse its cached residual. To prevent approximation errors from permanently contaminating the autoregressive KV cache, X-Cache identifies KV update chunks (the forward passes that write clean keys and values into the persistent cache) and unconditionally forces full computation on these chunks, cutting off error propagation. We implement X-Cache on X-world, a production multi-camera action-conditioned driving world model built on multi-block causal DiT with few-step denoising and rolling KV cache. X-Cache achieves 71% block skip rate with 2.6x wall-clock speedup while maintaining minimum degradation.

Flight diversions are rare but high-impact events in aviation, making their reliable prediction vital for both safety and operational efficiency. However, their scarcity in historical records impedes the training of machine learning models utilised to predict them. This study addresses this scarcity gap by investigating how generative models can augment historical flight data with synthetic diversion records to enhance model training and improve predictive accuracy. We propose a multi-objective optimisation framework coupled with automated hyperparameter search to identify optimal configurations for three deep generative models: Tabular Variational Autoencoder (TVAE), Conditional Tabular Generative Adversarial Network (CTGAN), and CopulaGAN, with the Gaussian Copula (GC) model serving as a statistical baseline. The quality of the synthetic data was examined through a six-stage evaluation framework encompassing realism, diversity, operational validity, statistical similarity, fidelity, and predictive utility. Results show that the optimised models significantly outperform their non-optimised counterparts, and that synthetic augmentation substantially improves diversion prediction compared to models trained solely on real data. These findings demonstrate the effectiveness of hyperparameter-optimised generative models for advancing predictive modelling of rare events in air transportation.

Recent segmentation models have demonstrated promising efficiency by aggressively reducing parameter counts and computational complexity. However, these models often struggle to accurately delineate fine lesion boundaries and texture patterns essential for early skin cancer diagnosis and treatment planning. In this paper, we propose MambaLiteUNet, a compact yet robust segmentation framework that integrates Mamba state space modeling into a U-Net architecture, along with three key modules: Adaptive Multi-Branch Mamba Feature Fusion (AMF), Local-Global Feature Mixing (LGFM), and Cross-Gated Attention (CGA). These modules are designed to enhance local-global feature interaction, preserve spatial details, and improve the quality of skip connections. MambaLiteUNet achieves an average IoU of 87.12% and average Dice score of 93.09% across ISIC2017, ISIC2018, HAM10000, and PH2 benchmarks, outperforming state-of-the-art models. Compared to U-Net, our model improves average IoU and Dice by 7.72 and 4.61 points, respectively, while reducing parameters by 93.6% and GFLOPs by 97.6%. Additionally, in domain generalization with six unseen lesion categories, MambaLiteUNet achieves 77.61% IoU and 87.23% Dice, performing best among all evaluated models. Our extensive experiments demonstrate that MambaLiteUNet achieves a strong balance between accuracy and efficiency, making it a competitive and practical solution for dermatological image segmentation. Our code is publicly available at: https://github.com/maklachur/MambaLiteUNet.

Multimodal Entity Linking (MEL) is a fundamental task in data management that maps ambiguous mentions with diverse modalities to the multimodal entities in a knowledge base. However, most existing MEL approaches primarily focus on optimizing instance-centric features and evidence, leaving broader forms of evidence and their intricate interdependencies insufficiently explored. Motivated by the observation that human expert decision-making process relies on multi-perspective judgment, in this work, we propose MSR-MEL, a Multi-perspective Evidence Synthesis and Reasoning framework with Large Language Models (LLMs) for unsupervised MEL. Specifically, we adopt a two-stage framework: (1) Offline Multi-Perspective Evidence Synthesis constructs a comprehensive set of evidence. This includes instance-centric evidence capturing the instance-centric multimodal information of mentions and entities, group-level evidence that aggregates neighborhood information, lexical evidence based on string overlap ratio, and statistical evidence based on simple summary statistics. A core contribution of our framework is the synthesis of group-level evidence, which effectively aggregates vital neighborhood information by graph. We first construct LLM-enhanced contextualized graphs. Subsequently, different modalities are jointly aligned through an asymmetric teacher-student graph neural network. (2) Online Multi-Perspective Evidence Reasoning leverages the power of LLM as a reasoning module to analyze the correlation and semantics of the multi-perspective evidence to induce an effective ranking strategy for accurate entity linking without supervision. Extensive experiments on widely used MEL benchmarks demonstrate that MSR-MEL consistently outperforms state-of-the-art unsupervised methods. The source code of this paper was available at: https://anonymous.4open.science/r/MSR-MEL-C21E/.

The analysis of neural representation has become an integral part of research aiming to better understand the inner workings of neural networks. While there are many different approaches to investigate neural representations, an important line of research has focused on doing so through the lens of intrinsic dimensions (IDs). Although this perspective has provided valuable insights and stimulated substantial follow-up research, important limitations of this approach have remained largely unaddressed. In this paper, we highlight a crucial discrepancy between theory and practice of IDs in neural representations, theoretically and empirically showing that common ID estimators are, in fact, not tracking the true underlying ID of the representation. We contrast this negative result with an investigation of the underlying factors that may drive commonly reported ID-related results on neural representation in the literature. Building on these insights, we offer a new perspective on ID estimation in neural representations.

We present ActuBench, a multi-agent LLM pipeline for the automated generation and evaluation of advanced actuarial assessment items aligned with the International Actuarial Association (IAA) Education Syllabus. The pipeline separates four LLM roles by adapter: one agent drafts items, one constructs distractors, a third independently verifies both stages and drives bounded one-shot repair loops, and a cost-optimized auxiliary agent handles Wikipedia-note summarization and topic labelling. The items, per-model responses and complete leaderboard are published as a browsable web interface at https://actubench.de/en/, allowing readers and practitioners to inspect individual items without a repository checkout. We evaluate 50 language models from eight providers on two complementary benchmarks -- 100 empirically hardest multiple-choice items and 100 open-ended items scored by an LLM judge -- and report three headline findings. First, multi-agent verification is load-bearing: the independent verifier flags a majority of drafted items on first pass, most of which the one-shot repair loop resolves. Second, locally-hosted open-weights inference sits on the cost-performance Pareto front: a Gemma~4 model running on consumer hardware and a Cerebras-hosted 120B open-weights model dominate the near-zero-cost region, with the latter within one item of the top of the leaderboard. Third, MCQ and LLM-as-Judge rankings differ meaningfully: the MCQ scaffold inflates the performance ceiling, and Judge-mode evaluation is needed to discriminate at the frontier.

Background: Osteoporosis and osteopenia are often undiagnosed until fragility fractures occur. Dual-energy X-ray absorptiometry (DXA) is the reference standard for bone mineral density (BMD) assessment, but access remains limited. Knee radiographs are obtained at high volume for osteoarthritis evaluation and may offer an opportunity for opportunistic bone-loss screening. Objective: To develop and evaluate a multi-task deep learning system for opportunistic bone-loss screening from routine knee radiographs without additional imaging or patient visits. Methods: We developed STR-Net, a multi-task framework for single-channel grayscale knee radiographs. The model includes a shared backbone, global average pooling feature aggregation, a shared neck, and a task-aware representation routing module connected to three task-specific heads: binary screening (Normal vs. Bone Loss), severity sub-classification (Osteopenia vs. Osteoporosis), and weakly coupled T-score regression with optional clinical variables. A sensitivity-constrained threshold optimization strategy (minimum sensitivity >= 0.86) was applied. The dataset included 1,570 knee radiographs, split at the patient level into training (n=1,120), validation (n=226), and test (n=224) sets. Results: On the held-out test set, STR-Net achieved an AUROC of 0.933, sensitivity of 0.904, specificity of 0.773, and AUPRC of 0.956 for binary screening. Severity sub-classification achieved an AUROC of 0.898. The T-score regression branch showed a Pearson correlation of 0.801 with DXA-measured T-scores in a pilot subset (n=31), with MAE of 0.279 and RMSE of 0.347. Conclusions: STR-Net enables single-pass bone-loss screening, severity stratification, and quantitative T-score estimation from routine knee radiographs. Prospective clinical validation is needed before deployment.

Audio carries richer information than text, including emotion, speaker traits, and environmental context, while also enabling lower-latency processing compared to speech-to-text pipelines. However, recent multimodal information retrieval research has predominantly focused on images, largely overlooking audio, especially in the setting of interleaved audio-text contextual retrieval. In this work, we introduce the Audio-Text Interleaved contextual Retrieval (ATIR) task, where queries can alternate between audio and text modalities. We construct an ATIR benchmark by integrating several Automatic Speech Recognition (ASR), QA, and retrieval datasets, ultimately unifying four types of contextual retrieval tasks. This benchmark substantially addresses the limitations of existing audio retrieval datasets in semantic retrieval. To study this task, we evaluate several off-the-shelf retrievers and train our ATIR model based on a Multimodal Large Language Model (MLLM). We further introduce a novel token compression mechanism that is orthogonal to existing compression methods, thereby alleviating the issue of excessive audio tokens in MLLM-based ATIR models. Experimental results demonstrate that our ATIR model achieves substantial improvements over strong baselines.

Automated feature generation extracts informative features from raw tabular data without manual intervention and is crucial for accurate, generalizable machine learning. Traditional methods rely on predefined operator libraries and cannot leverage task semantics, limiting their ability to produce diverse, high-value features for complex tasks. Recent Large Language Model (LLM)-based approaches introduce richer semantic signals, but still suffer from a restricted feature space due to fixed generation patterns and from the absence of feedback from the learning objective. To address these challenges, we propose a Memory-Augmented LLM-based Multi-Agent System (\textbf{MALMAS}) for automated feature generation. MALMAS decomposes the generation process into agents with distinct responsibilities, and a Router Agent activates an appropriate subset of agents per iteration, further broadening exploration of the feature space. We further integrate a memory module comprising procedural memory, feedback memory, and conceptual memory, enabling iterative refinement that adaptively guides subsequent feature generation and improves feature quality and diversity. Extensive experiments on multiple public datasets against state-of-the-art baselines demonstrate the effectiveness of our approach. The code is available at https://github.com/fxdong24/MALMAS

Accurate early prediction of Acute Kidney Injury (AKI) is critical for timely clinical intervention. However, existing deep learning models struggle with irregularly sampled data and suffer from the opaque "black-box" nature of sequential architectures, strictly limiting clinical trust. To address these challenges, we propose CT-Former, integrating continuous-time modeling with a Causal-Transformer. To handle data irregularity without biased artificial imputation, our framework utilizes a continuous-time state evolution mechanism to naturally track patient temporal trajectories. To resolve the black-box problem, our Causal-Attention module abandons uninterpretable hidden state aggregation. Instead, it generates a directed structural causal matrix to identify and trace the exact historical onset of severe physiological shocks. By establishing clear causal pathways between historical anomalies and current risk predictions, CT-Former provides native clinical interpretability. Training follows a decoupled two-stage protocol to optimize the causal-fusion process independently. Extensive experiments on the MIMIC-IV cohort (N=18,419) demonstrate that CT-Former significantly outperforms state-of-the-art baselines. The results confirm that our explicitly transparent architecture offers an accurate and trustworthy tool for clinical decision-making.

Instruction-based image editing (IIE) aims to modify images according to textual instructions while preserving irrelevant content. Despite recent advances in diffusion transformers, existing methods often suffer from over-editing, introducing unintended changes to regions unrelated to the desired edit. We identify that this limitation arises from the lack of an explicit mechanism for edit localization. In particular, different editing operations (e.g., addition, removal and replacement) induce distinct spatial patterns, yet current IIE models typically treat localization in a task-agnostic manner. To address this limitation, we propose a training-free, task-aware edit localization framework that exploits the intrinsic source and target image streams within IIE models. For each image stream, We first obtain attention-based edit cues, and then construct feature centroids based on these attentive cues to partition tokens into edit and non-edit regions. Based on the observation that optimal localization is inherently task-dependent, we further introduce a unified mask construction strategy that selectively leverages source and target image streams for different editing tasks. We provide a systematic analysis for our proposed insights and approaches. Extensive experiments on EdiVal-Bench demonstrate our framework consistently improves non-edit region consistency while maintaining strong instruction-following performance on top of powerful recent image editing backbones, including Step1X-Edit and Qwen-Image-Edit.

A common strategy in transfer learning is few shot fine-tuning, but its success is highly dependent on the quality of samples selected as training examples. Active learning methods such as uncertainty sampling and diversity sampling can select useful samples. However, under extremely low-resource and class-imbalanced conditions, they often favor outliers rather than truly informative samples, resulting in degraded performance. In this paper, we introduce RADS (Reinforcement Adaptive Domain Sampling), a robust sample selection strategy using reinforcement learning (RL) to identify the most informative samples. Experimental evaluations on several real world clinical datasets show our sample selection strategy enhances model transferability while maintaining robust performance under extreme class imbalance compared to traditional methods.

Anomaly detection in tabular data is challenging due to high dimensionality, complex feature dependencies, and heterogeneous noise. Many existing methods rely on proximity-based cues and may miss anomalies caused by violations of complex feature dependencies. Dependency-based anomaly detection provides a principled alternative by identifying anomalies as violations of dependencies among features. However, existing methods often struggle to model such dependencies robustly and to scale to high-dimensional data with complex dependency structures. To address these challenges, we propose uLEAD-TabPFN, a dependency-based anomaly detection framework built on Prior-Data Fitted Networks (PFNs). uLEAD-TabPFN identifies anomalies as violations of conditional dependencies in a learned latent space, leveraging frozen PFNs for dependency estimation. Combined with uncertainty-aware scoring, the proposed framework enables robust and scalable anomaly detection. Experiments on 57 tabular datasets from ADBench show that uLEAD-TabPFN achieves particularly strong performance in medium- and high-dimensional settings, where it attains the top average rank. On high-dimensional datasets, uLEAD-TabPFN improves the average ROC-AUC by nearly 20\% over the average baseline and by approximately 2.8\% over the best-performing baseline, while maintaining overall superior performance compared to state-of-the-art methods. Further analysis shows that uLEAD-TabPFN provides complementary anomaly detection capability, achieving strong performance on datasets where many existing methods struggle.

Text-guided molecular design is a key capability for AI-driven drug discovery, yet it remains challenging to map sequential natural-language instructions with non-linear molecular structures under strict chemical constraints. Most existing approaches, including RAG, CoT prompting, and fine-tuning or RL, emphasize a small set of ad-hoc reasoning perspectives implemented in a largely one-shot generation pipeline. In contrast, real-world drug discovery relies on dynamic, multi-perspective critique and iterative refinement to reconcile semantic intent with structural feasibility. Motivated by this, we propose Mol-Debate, a generation paradigm that enables such dynamic reasoning through an iterative generate-debate-refine loop. We further characterize key challenges in this paradigm and address them through perspective-oriented orchestration, including developer-debater conflict, global-local structural reasoning, and static-dynamic integration. Experiments demonstrate that Mol-Debate achieves state-of-the-art performance against strong general and chemical baselines, reaching 59.82% exact match on ChEBI-20 and 50.52% weighted success rate on S$^2$-Bench. Our code is available at https://github.com/wyuzh/Mol-Debate.